From: A 90 day chronic toxicity study of Nigerian herbal preparation DAS-77 in rats
Treatment | Dose (mg/kg) | Reversibility study | ||||
---|---|---|---|---|---|---|
Ā | Ā | Na+ (mmol/L) | K+(mmol/L) | Clā (mmol/L) | HCO3 ā(mmol/L) | Ca2+(mg/dl) |
Distilled water | (10 ml/kg) | 154.90āĀ±ā1.29 | 5.19āĀ±ā0.17 | 104.50āĀ±ā0.93 | 11.38āĀ±ā0.68 | 1.18āĀ±ā0.05 |
DAS-77 | 80 | 154.80āĀ±ā0.64 | 4.99āĀ±ā0.17 | 106.70āĀ±ā0.71 | 12.33āĀ±ā0.88 | 1.12āĀ±ā0.05 |
DAS-77 | 400 | 153.30āĀ±ā0.80 | 5.09āĀ±ā0.15 | 105.80āĀ±ā1.07 | 11.63āĀ±ā0.60 | 1.15āĀ±ā0.04 |
DAS-77 | 2000 | 158.00āĀ±ā1.07 | 5.10āĀ±ā0.15 | 108.20āĀ±ā1.17 | 11.83āĀ±ā0.60 | 1.08āĀ±ā0.05 |