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Table 5 Urin analysis in male and female dogs

From: Assessment of anti-depressant effect of nelumbinis semen on rats under chronic mild stress and its subchronic oral toxicity in rats and beagle dogs

Groups (mg/kg/day) male
  0 500 1000 2000 4000
  Before After Before After Before After Before After Before After
GLU +/− +/− - - - - - - - -
BIL 1+ - - 1+ - - 1+ - - -
KET - - - - - - - - - -
SG 1.020 ≤1.005 1.015 1.015 1.010 ≥1.030 1.010 ≤1.005 ≤1.005 ≤1.005
pH 7.0 ≥9.0 8.0 8.0 8.0 7.0 8.5 ≥9.0 ≥9.0 8.5
PRO 1+ 3+ 1+ 2+ 3+ 2+ 1+ +/− 3+ +/−
URO 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 1.0 0.1
NIT - - - - - - - - - -
OB - - - - - - 2+ 1+ - 1+
WBC 2+ 2+ 1+ 2+ 1+ +/− 2+ 3+ 2+ 3+
Groups (mg/kg/day) female
  0 500 1000 2000 4000
  Before After Before After Before After Before After Before After
GLU - - - - - - - - - -
BIL - - - - - - - - - -
KET - - - - - - - - - -
SG ≤1.005 ≤1.005 ≥1.030 ≤1.005 ≥1.030 ≤1.005 ≥1.030 ≤1.005 ≥1.030 ≤1.005
pH 8.5 ≥9.0 6.5 ≥9.0 6.5 8.5 6.5 8.0 6.5 ≥9.0
PRO - +/− 2+ 1+ 2+ 3+ 1+ - 2+ 2+
URO 0.1 0.1 0.1 0.1 1.0 0.1 0.1 0.1 0.1 0.1
NIT - - - - - - - - - -
OB - - - - - - - - - 2+
WBC - +/− - - - +/− - 1+ +/− +/−
  1. GLU = Glucose, BIL = bilirubin, KET = ketone body, SG = specific gravity, OB = occult blood, pH, PRO = protein, URO = urobilinogen, NIT = nitrite and WBC = leukocyte.