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Table 1 Effect of roots bark extract of C. sieberiana on mucosal PGE 2 and 6-keto PGF levels and serum sPLA 2 activity in guinea pigs

From: Antioxidant and gastric cytoprotective prostaglandins properties of Cassia sieberiana roots bark extract as an anti-ulcerogenic agent

Treatment Dose (mg/kg) PGE2(pg/mL) (Mean ± S.E.M) 6-keto PGF(pg/mL) (Mean ± S.E.M) sPLA2activity (nmol/min/mL) (Mean ± S.E.M)
Control vehicle 0.17 ± 0.02 2.10 ± 0.19 26.44 ± 0.69
Extract 250 0.23 ± 0.01* 2.69 ± 0.08* 20.84 ± 0.65
500 0.28 ± 0.02 3.39 ± 0.34* 18.16 ± 0.68
750 0.31 ± 0.02 3.95 ± 0.19 10.52 ± 0.52
  1. * p < 0.05, statistically significant relative to control.
  2. p < 0.01, statistically significant relative to control.
  3. p < 0.001, statistically significant relative to control.