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Table 1 Effect of Qur and/or Arg treatment on serum inflammatory markers level in intoxicated rats with a low dose of n-ZnO particles

From: Role of quercetin and arginine in ameliorating nano zinc oxide-induced nephrotoxicity in rats

Parameters

Control

n-ZnO

Qur

Arg

Qur + Arg

TNF- α (pg/ml)

242.7 ± 6.1

361.6 ± 9.2a

299.5 ± 3.1*b # #

276.12 ± 4.05*b

300.6 ± 4.1*b # #

CRP (ng/ml)

3.16 ± 0.1

4.4 ± 0.20 a

3.4 ± 0.04*c

3.3 ± 0.04*c

3.1 ± 0.7* # #

IL-6 (pg/ml)

31 ± 2.098

44.33 ± 1.2a

42.86 ± 0.49 a#

35.3 ± .81 a*

35.66 ± 1.21 a*

  1. Data are presented as mean ± S.D. from 10 rats, a P ≤ 0.001, b P ≤ 0.01, c P ≤ 0.05 compared with the normal group, * P ≤ 0.001 compared with the n-ZnO-intoxicated group, # P ≤ 0.001, ## P ≤ 0.01 compared with the combination group, respectively, using ANOVA followed by Bonferroni as a post-ANOVA test.