ARE decreased the expression of adhesion molecules in the endothelium of apoE
mice. A. ARE treatment suppressed the levels of VCAM-1 and ICAM-1 in the aortic endothelium of apoE−/− mice. Double-immunofluorescence staining (n = 4–5 sections per tissue, at least three sites of analysis per slide). B. The relative fluorescence intensity of VCAM-1 and ICAM-1 in the endothelium of apoE −/− mice. *P < 0.01 vs control. Scale bars: 80 μm.