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Table 1 Effects of HQD on fibrotic grade and hydroxyproline (Hyp) content in DMN-induced liver fibrosis of rats

From: Huangqi decoction inhibits apoptosis and fibrosis, but promotes Kupffer cell activation in dimethylnitrosamine-induced rat liver fibrosis

Group

n

Hyp content ug/g( x ¯ ±s)

Fibrotic grade

Confidence interval

   

0

I

II

III

IV

 

Control

10

179.36 ± 31.29

10

0

0

0

0

(-0.110,0.228)

2 weeks DMN

6

289.06 ± 66.00

0

0

4

2

0

(0.051,0.486)

DMN-water

12

641.71 ± 187.81

0

0

0

3

9

(0.586,0.894)

DMN-HQD

12

559.04 ± 163.02

0

0

0

8

4

(0.580,0.734)

  1. grade 0: normal; grade 1: very slight; grade 2: slight; grade 3: moderate; grade 4: severe. Data are expressed as numbers of animals with each fibrotic grade. P < 0.05 P < 0.01 (vs DMN- water) P < 0.05 P < 0.01 (vs 2 weeks DMN).