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Table 1 Effects of HQD on fibrotic grade and hydroxyproline (Hyp) content in DMN-induced liver fibrosis of rats

From: Huangqi decoction inhibits apoptosis and fibrosis, but promotes Kupffer cell activation in dimethylnitrosamine-induced rat liver fibrosis

Group n Hyp content ug/g( x ¯ ±s) Fibrotic grade Confidence interval
    0 I II III IV  
Control 10 179.36 ± 31.29 10 0 0 0 0 (-0.110,0.228)
2 weeks DMN 6 289.06 ± 66.00 0 0 4 2 0 (0.051,0.486)
DMN-water 12 641.71 ± 187.81 0 0 0 3 9 (0.586,0.894)
DMN-HQD 12 559.04 ± 163.02 0 0 0 8 4 (0.580,0.734)
  1. grade 0: normal; grade 1: very slight; grade 2: slight; grade 3: moderate; grade 4: severe. Data are expressed as numbers of animals with each fibrotic grade. P < 0.05 P < 0.01 (vs DMN- water) P < 0.05 P < 0.01 (vs 2 weeks DMN).