Figure 2

Inhibitory effects of Tan IIA on the proliferation of U-937 cells. (A) The percentage of cells that survived gradually decreased in a time- and dose-dependent manner after Tan IIA treatment. (B) Morphological changes of U-937 cells without (DMSO) and with Tan IIA treatment. The U-937 cells were treated with Tan IIA and the morphology of cell apoptosis was examined by phase-contrast microscopy. The magnification of the squared regions is shown to the right. Several cells undergoing apoptosis are indicated by arrows.