Table 5 Effects of extracts from A. salicina on the mutagenicity induced by MMS and 2-AA in S. typhimurium TA102 assay system respectively in the absence and in the presence of S9
TA102 | |||||
|---|---|---|---|---|---|
Extracts | Dose (µg/plate) | -S9 | +S9 | ||
| Â | Â | Nb Revertants/plate | % inhibition of mutagenesis | Nb Revertants/plate | % inhibition of mutagenesis |
Spontaneous | - | 175 ± 10 | - | 235 ± 12 | - |
PC | - | 1721 ± 24 | - | 652 ± 10 | - |
Aqueous extract | 5 | NT | NT | 600 ± 3 | 44.6* |
|  | 10 | NT | NT | 580 ± 8 | 17 |
|  | 25 | NT | NT | 466 ± 5 | 12.4 |
| Â | 50 | 477 | 80.5* | T | - |
| Â | 250 | 398 | 85.6* | T | - |
| Â | 500 | 387 | 86.3* | T | - |
TOF extract | 5 | NT | NT | 516 ± 15 | 32.6* |
|  | 10 | NT | NT | 520 ± 17 | 31.6* |
|  | 25 | NT | NT | 619 ± 14 | 8 |
| Â | 50 | 377 | 86.9* | T | - |
| Â | 250 | 354 | 88.4* | T | - |
| Â | 500 | 276 | 93.5* | T | - |
Methanolic extract | 5 | NT | NT | 516 ± 9 | 32.6* |
|  | 10 | NT | NT | 520 ± 3 | 31* |
|  | 25 | NT | NT | 572 ± 9 | 20 |
| Â | 50 | 455 | 81.8* | T | - |
| Â | 250 | 356 | 88.3* | T | - |
| Â | 500 | 345 | 89* | T | - |