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Table 3 Effects of extracts from A. salicina on the mutagenicity induced by NOPD (10 μg/plate) and B(a)P (7.5 μg/plate) in S. typhimurium TA98 assay system respectively in the absence and in the presence of S9

From: Polar extracts from (Tunisian) Acacia salicina Lindl. Study of the antimicrobial and antigenotoxic activities

  

TA98

  

-S9

+S9

Extracts

Dose

(µg/plate)

Nb

Revertants/plate

% inhibition of mutagenesis

Nb Revertants/plate

% inhibition of mutagenesis

Spontaneous

-

27 ± 6

-

36 ± 2

-

PC

-

723 ± 21

-

122 ± 11

-

Aqueous extract

50

235 ± 11

70.2*

66

65.1*

 

250

127 ± 10

85.6*

49

84.8*

 

500

87 ± 09

91.4*

50

83.7*

TOF extract

50

225 ± 08

71.6*

45

89.5*

 

250

88 ± 06

91.2*

41

94.2*

 

500

31 ± 03

99.4*

37

97.6*

Methanolic extract

50

207 ± 06

74.2*

65

66.3*

 

250

122 ± 04

86.4*

61

71*

 

500

67 ± 05

94.3*

41

95.2*

  1. Positive control (PC): TA98/-S9, NOPD (10 μg/plate); TA98/+S9, B(a)P (7.5 μg/plate).