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Table 3 The average integration optic density (IOD) values of positive staining areas of α-SMA, Alb, CK 7, and TGFβ1 in liver tissues (mean ± S.D.)

From: Ingredients of Huangqi decoction slow biliary fibrosis progression by inhibiting the activation of the transforming growth factor-beta signaling pathway

group n α-SMA Alb CK 7 TGFβ1
sham control group 8 0.02 ± 0.01## 0.53 ± 0.03## 0.00 ± 0.00## 0.03 ± 0.01##
1 week BDL alone group 8 0.03 ± 0.01## 0.34 ± 0.02**## 0.06 ± 0.02**## 0.07 ± 0.02*##
2 week BDL alone group 8 0.06 ± 0.01**## 0.30 ± 0.02**## 0.10 ± 0.02**## 0.11 ± 0.03**##
3 week BDL alone group 8 0.14 ± 0.02**## 0.24 ± 0.02**## 0.16 ± 0.02**## 0.15 ± 0.03**##
4 week BDL alone group 8 0.27 ± 0.03**## 0.19 ± 0.02**## 0.19 ± 0.01** 0.17 ± 0.02**
5 week BDL alone group 10 0.36 ± 0.03** 0.14 ± 0.02** 0.21 ± 0.02** 0.20 ± 0.02**
IHQD group 14 0.11 ± 0.02**## 0.28 ± 0.01**## 0.15 ± 0.02**## 0.15 ± 0.03**##
  1. Note: Compared with sham control group, *p < 0.05, **p < 0.01; compared with 5 week BDL alone group, #p < 0.05, ##p < 0.01. α-SMA α-smooth muscle actin, Alb albumin, CK 7 cytokeratin 7, TGFβ1 transforming growth factor β1