Serum lipid levels of sham operated control (SHAM) and ovariectomized (OVX) rats treated with or without C. comosa hexane extract or compound 049. Animals are as described in legend of Figure 2. (A) total; (B) high-density lipoprotein (HDL) cholesterol; (C) low-density lipoprotein (LDL) cholesterol; (D) ratio of HDL to total cholesterol (HDL/total); and (E) ratio of LDL to total cholesterol (LDL/total). Values are reported as the mean ± SE for 8 animals/group. *P < 0.05 vs. SHAM group; † P < 0.05 vs. OVX group.