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Table 3 Effects of Bersama engleriana on blood glucose in nicotinamide/streptozotocin-induced type 2 diabetic rats

From: Hypoglycemic and hypolipidemic effects of Bersama engleriana leaves in nicotinamide/streptozotocin-induced type 2 diabetic rats

Groups

Fasting blood glucose level (mg/dl)

  

Week of treatment

 

At the time of grouping

Week 0

Week 1

Week 2

Week 4

Control

97.80 ± 02.97

69.00 ± 07.40a

75.8 ± 09.05a

81.00 ± 04.25a

62.00 ± 03.45a

Untreated diabetic

97.40 ± 04.54

270.80 ± 81.14a***

244.40 ± 69.28a***

202.60 ± 55.54a*

203.00 ± 46.62a**

Diabetic + Glibenclamide (0.25 mg/kg)

86.40 ± 06.53

227.80 ± 83.62a**

146.40 ± 51.05ad

98.20 ± 09.28bd

94.20 ± 11.20bd

Diabetic + Aqueous extract (300 mg/kg)

95.40 ± 05.08

156.60 ± 20.76#a

121.80 ± 06.80#a

109.60 ± 07.15a

96.60 ± 02.67a

Diabetic + Aqueous extract (600 mg/kg)

91.00 ± 06.47

303.80 ± 41.86a***

183.60 ± 33.96bd

119.00 ± 04.63cd

98.00 ± 07.52c

Diabetic + Methanolic extract (300 mg/kg)

90.20 ± 04.18

181.80 ± 48.41a*

114.00 ± 15.71#a

86.60 ± 07.35#a

83.60 ± 08.18#a

Diabetic + Methanolic extract (600 mg/kg)

90.20 ± 03.38

454.00 ± 10.93a*** ###

288.40 ± 45.75b***

167.60 ± 42.28c

89.40 ± 06.23#c

  1. Values are means ± SEM; number of animals per group = 6.
  2. On the same line, values assigned with the same letter are not significantly different.
  3. Within a column, *: p<0.05; **: p <0.01; *** p <0.001: significantly different compared to control.
  4. #: p <0.05; ###: p <0.001: significantly different compared to untreated diabetic.