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Table 3 The effect of selected plant extracts on the chemical properties of sickle cell blood

From: Solenostemon monostachyus, Ipomoea involucrata and Carica papaya seed oil versus Glutathione, or Vernonia amygdalina: Methanolic extracts of novel plants for the management of sickle cell anemia disease

Treatment Fe2+/Fe3+ Ratio Hemoglobin concentration (%) Hb/Met-Hb ratio (× 10-1) Sickle cell polymerization inhibition (× 10-4) (Unit/min)
Male Female Male Female Male Female Male Female
Control 9.94 ± 5.07 5.34 ± 1.40 NT NT NT NT 8.50 ± 7.00 0.00 ± 0.00
Vernonia amygdalina 4.49 ± 1.29 3.66 ± 1.53 15.34 ± 7.34 29.52 ± 16.01 0.91 ± 0.47 4.59 ± 3.44 16.43 ± 4.12 21.50 ± 6.61
Ipomoea involucrata 3.45 ± 1.19 2.78 ± 1.82 34.25 ± 8.59 51.99 ± 26.89 1.01 ± 0.47 2.69 ± 1.85 6.00 ± 4.29 18.50 ± 10.12
Solenostemon monostachyus 2.33 ± 0.49 1.48 ± 0.33 43.16 ± 17.51 132.78 ± 97.61 0.88 ± 0.31 1.85 ± 0.49 41.33 ± 9.28 94.00 ± 17.28
Carica papaya seed oil 4.52 ± 1.83 3.00 ± 0.96 25.33 ± 8.37 34.22 ± 18.26 1.44 ± 0.84 2.72 ± 1.74 14.50 ± 9.69 15.50 ± 6.27
  1. Data expressed as mean ± SD (n = 10). Hb = hemoglobin; Met-Hb= methemoglobin; NT = not tested.