Solenostemon monostachyus, Ipomoea involucrata and Carica papaya seed oil versus Glutathione, or Vernonia amygdalina: Methanolic extracts of novel plants for the management of sickle cell anemia disease

Table 3 The effect of selected plant extracts on the chemical properties of sickle cell blood

Treatment	Fe²⁺/Fe³⁺ Ratio		Hemoglobin concentration (%)		Hb/Met-Hb ratio (× 10^-1)		Sickle cell polymerization inhibition (× 10^-4) (Unit/min)
Treatment	Male	Female	Male	Female	Male	Female	Male	Female
Control	9.94 ± 5.07	5.34 ± 1.40	NT	NT	NT	NT	8.50 ± 7.00	0.00 ± 0.00
Vernonia amygdalina	4.49 ± 1.29	3.66 ± 1.53	15.34 ± 7.34	29.52 ± 16.01	0.91 ± 0.47	4.59 ± 3.44	16.43 ± 4.12	21.50 ± 6.61
Ipomoea involucrata	3.45 ± 1.19	2.78 ± 1.82	34.25 ± 8.59	51.99 ± 26.89	1.01 ± 0.47	2.69 ± 1.85	6.00 ± 4.29	18.50 ± 10.12
Solenostemon monostachyus	2.33 ± 0.49	1.48 ± 0.33	43.16 ± 17.51	132.78 ± 97.61	0.88 ± 0.31	1.85 ± 0.49	41.33 ± 9.28	94.00 ± 17.28
Carica papaya seed oil	4.52 ± 1.83	3.00 ± 0.96	25.33 ± 8.37	34.22 ± 18.26	1.44 ± 0.84	2.72 ± 1.74	14.50 ± 9.69	15.50 ± 6.27

Data expressed as mean ± SD (n = 10). Hb = hemoglobin; Met-Hb= methemoglobin; NT = not tested.

ISSN: 2662-7671