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Table 2 Mean flow-mediated dilation, brachial artery diameter, velocity-time integral, and blood pressure by dose (N = 21)

From: Effect of hawthorn standardized extract on flow mediated dilation in prehypertensive and mildly hypertensive adults: a randomized, controlled cross-over trial

  Placebo 1000 mg 1500 mg 2500 mg p-value 1
FMD      
   Δ BAD, mm 0.18 (0.14) 0.16 (0.12) 0.14 (0.13) 0.17 (0.12) 0.54
   FMD, % 5.3 (4.3) 5.0 (4.1) 4.3 (4.0) 4.9 (4.1) 0.59
BAD, mm      
   Resting 3.5 (0.7) 3.5 (0.8) 3.6 (0.8) 3.5 (0.8) 0.74
   Hyperemia 3.7 (0.7) 3.6 (0.8) 3.7 (0.8) 3.7 (0.8) -
VTI, cm 85.7 (20.8) 91.3 (19.5) 82.0 (21.4) 83.9 (18.0) 0.31
Blood Pressure, mm Hg      
   Systolic 129.4 (8.1) 130.7 (10.7) 131.1 (13.6) 132.0 (10.0) 0.33
   Diastolic 82.8 (7.3) 81.8 (7.8) 83.0 (9.1) 82.3 (7.7) 0.72
  1. 1 p-value for modified linear contrast assessing dose-response from mixed effects linear model controlling for period and baseline response. Models for FMD also controlled for resting BAD.
  2. All values expressed as mean (SD).
  3. FMD - flow mediated dilation, BAD - brachial artery diameter, VTI - velocity-time integral
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