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Table 3 Effect of PF on TNF-α and IL-1β levels in the serum in DMN-induced rat liver fibrosis ( x ¯ ± s )

From: Paeoniflorin regulates macrophage activation in dimethylnitrosamine-induced liver fibrosis in rats

Group (number)

TNF-α (pg/L)

IL-1β (pg/L)

Normal (5)

35.44±5.64

26.70±3.56

2-week DMN (3)

896.51±78.06

954.71±75.28

DMN-water (5)

758.72±61.54

647.66±95.54

DMN-PF (5)

446.95±42.90

471.34±26.67

DMN-GdCl3 (5)

708.03±78.84

705.63±99.46

  1. p<0.05 versus 2-week DMN rats; p<0.05 versus DMN-water rats. Bonferroni’s multiple comparison test was used for group comparisons in TNF-α and IL-1β.