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Table 1 Effects of PF on body weight and main organs weight in DMN-induced rat liver fibrosis ( x ¯ ± s )

From: Paeoniflorin regulates macrophage activation in dimethylnitrosamine-induced liver fibrosis in rats

Group (number)

Body weight (g)

Liver weight (g)

Spleen weight (g)

Heart weight (g)

Lung weight (g)

Kidney weight (g)

Brain weight (g)

2-week normal(3)

199.33±9.45

6.81±0.61

0.54±0.11

0.56±0.09

0.75±0.12

1.16±0.10

1.04±0.02

2-week DMN(3)

180.33±0.55

7.67±0.47

0.77±0.06⋆

0.50±0.01▴

0.93±0.06⋆

1.37±0.06

1.10±0.00

4-week normal(7)

273.90±12.29▴

10.03±0.86▴

0.59±0.09⋆

0.81±0.07▴

1.00±0.00

1.64±0.15▴

1.17±0.05

DMN-water(5)

201.50±17.81

5.92±1.64

1.38±0.30☆

0.72±0.07△

1.05±0.11☆

1.43±0.08

1.20±0.10

DMN-PF(7)

208.87±18.46

6.45±1.21

1.13±0.22

0.66±0.05

1.00±0.00

1.46±0.13

1.17±0.05

DMN-GdCl3(6)

183.48±13.99▴

4.73±0.41

1.11±0.08

0.63±0.08▴

1.07±0.10

1.65±0.26▴

1.13±0.12

  1. â–³ p<0.05 versus the same period in 2-week DMN rats; â–´ p<0.05 versus the same period in DMN-water rats.
  2. Bonferroni’s multiple comparison test were used for group comparisons in body weight, liver weight, heart weight, and kidneys weight.
  3. ☆ p<0.05 versus the same period in 2-week DMN rats; ⋆ p<0.05 versus the same period in DMN-water rats. Kruskal-Wallis test were used for group comparisons in liver weight, spleen weight, lung weights, and brain weight.