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Table 2 Bax/Bcl-2 ratio of mRNA expression

From: Modulation of apoptosis in human hepatocellular carcinoma (HepG2 cells) by a standardized herbal decoction of Nigella sativa seeds, Hemidesmus indicus roots and Smilax glabra rhizomes with anti- hepatocarcinogenic effects

Dose of the decotion Bax/Bcl-2
  12 h 24 h 48 h
Control 0.484 0.489 0.468
75 μg/ml 0.603 0.663 0.827
150 μg/ml 0.758 0.920 1.020
300 μg/ml 1.074 1.220 1.410
600 μg/ml 1.660 1.886 2.180
1200 μg/ml 2.254 2.792 3.857
  1. Bax/Bcl-2 ratio was up regulated in a time and dose dependent manner
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