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Table 1 Effect of C. sieberiana (CS) root bark extract on ulcer index in ethanol-induced gastric ulcer rats

From: Anti-ulcerogenic activity of the root bark extract of the African laburnum “Cassia sieberiana” and its effect on the anti-oxidant defence system in rats

Treatment Dose (mg/kg body wt.) Mean Ulcer index [Score 0–10](Mean ± SEM)
Baseline (intact) - -
Ulcer control Vehicle 8.00 ± 0.37
CS-extract 500 5.80 ± 0.31a
750 4.00 ± 0.37b, c
1000 1.17 ± 0.17b, d
Ranitidine 50 1.50 ± 0.22b
  1. a p< 0.05 compared with ulcer control; b p< 0.001 compared with ulcer control; c p< 0.05 compared with CS-500; d p< 0.01 compared with CS-750; Values are Mean ± SEM of 6 animals. Statistical significance was determined by one-way analysis of variance (ANOVA) followed by Dunnett’s post hoc t test.