A comparative study on the hepatoprotective action of bear bile and coptidis rhizoma aqueous extract on experimental liver fibrosis in rats

Table 8 Semi-quantitative histological analysis on effect of drug intervention against liver fibrosis induced by Alcohol in rats (n = 7, $\bar{x} \pm s$ )

Group	Hepatocyte death	Inflammatory cell infiltration	Fibrosis	Combined score
Normal	0.3 ± 0.2	3.0 ± 0.1	0.1 ± 0.1	0.3 ± 0.1
Model	4.1 ± 0.7^△△	3.3 ± 0.6^△△	4.3 ± 0.7^△△	4.0 ± 0.6^△△
Sylimarin	1.5 ± 0.7^**	1.6 ± 0.5^**	3.2 ± 0.5	2.6 ± 0.5^*
BBR	1.3 ± 0.3^**	1.4 ± 0.5^**	1.8 ± 0.3^**	2.2 ± 0.5^**
CRAE	1.5 ± 0.7^**	1.3 ± 0.6^**	2.2 ± 0.5^**	2.5 ± 0.4^*
BB	1.6 ± 0.5^**	1.3 ± 30.5^**	1.2 ± 0.4^**	2.0 ± 0.4^**
TUDCA	0.9 ± 0.4^**	0.7 ± 0.3^**	0.8 ± 0.3^**	1.0 ± 0.4^**

^△p < 0.05 when compared with normal group; ^△△p < 0.01 when compared with normal group; ^*p < 0.05 when compared with model group; ^**p < 0.01 when compared with model group.

ISSN: 2662-7671