A comparative study on the hepatoprotective action of bear bile and coptidis rhizoma aqueous extract on experimental liver fibrosis in rats

Table 6 Analysis on effect of drug intervention against fibrogenesis induced by bile duct-ligation in rats (n = 7, $\bar{x} \pm s$ )

Group	Sample (n)	Fibrosis phase				Fibrotic area within 1.5 mm²(mm2)
		0	1	2	3
Normal	7	7	0	0	0	0
Shamed	7	7	0	0	0	0
Model	7	0	2	1	4	0.88 ± 0.46^△△
Silymarin	7	0	3	2	2	0.62 ± 0.21^*
Berberine	7	0	4	2	1	0.38 ± 0.25^**
CRAE	7	0	4	2	1	0.55 ± 0.21^*
Bear Bile	7	0	5	1	1	0.32 ± 0.19^**
TUDCA	7	0	3	1	3	0.61 ± 0.32

^△p < 0.05 when compared with normal group; ^△△p < 0.01 when compared with normal group; ^*p < 0.05 when compared with model group; ^**p < 0.01 when compared with model group.

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