A comparative study on the hepatoprotective action of bear bile and coptidis rhizoma aqueous extract on experimental liver fibrosis in rats

Table 5 Analysis on effect of drug intervention against fibrogenesis induced by CCl ₄ in rats (n = 7, $\bar{x} \pm s$ )

Group	Sample (n)	Fibrosis phase					Fibrotic area within 1.5 mm²(mm²)
		S0	S1	S2	S3	S4
Nomral	7	7	0	0	0	0	0
Model	7	0	0	2	4	1	0.090 ± 0.021^△△
Silymarin	7	0	2	3	2	0	0.067 ± 0.046
Berberine	7	0	3	2	2	0	0.041 ± 0.020^**
CRAE	7	0	2	3	2	0	0.056 ± 0.021^*
Bear Bile	7	0	3	3	1	0	0.048 ± 0.046^*
TUDCA	7	0	2	3	0	2	0.065 ± 0.047

^△p < 0.05 when compared with normal group; ^△△p < 0.01 when compared with normal group; ^*p < 0.05 when compared with model group; ^**p < 0.01 when compared with model group.

ISSN: 2662-7671