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Table 5 Analysis on effect of drug intervention against fibrogenesis induced by CCl 4 in rats (n = 7, x ¯ ± s )

From: A comparative study on the hepatoprotective action of bear bile and coptidis rhizoma aqueous extract on experimental liver fibrosis in rats

Group Sample (n) Fibrosis phase Fibrotic area within 1.5 mm2(mm2)
   S0 S1 S2 S3 S4  
Nomral 7 7 0 0 0 0 0
Model 7 0 0 2 4 1 0.090 ± 0.021
Silymarin 7 0 2 3 2 0 0.067 ± 0.046
Berberine 7 0 3 2 2 0 0.041 ± 0.020**
CRAE 7 0 2 3 2 0 0.056 ± 0.021*
Bear Bile 7 0 3 3 1 0 0.048 ± 0.046*
TUDCA 7 0 2 3 0 2 0.065 ± 0.047
  1. p < 0.05 when compared with normal group; p < 0.01 when compared with normal group; *p < 0.05 when compared with model group; **p < 0.01 when compared with model group.