Skip to main content

Table 10 Semi-quantitative histological analysis on effect of drug intervention against liver fibrosis induced by BDL in rats(n = 7, x ¯ ± s )

From: A comparative study on the hepatoprotective action of bear bile and coptidis rhizoma aqueous extract on experimental liver fibrosis in rats

Group

Hepatocyte death

Inflammatory cell infiltration

Fibrosis

Combined score

Normal

0.5 ± 0.3

0.3 ± 0.3

0.5 ± 0.1

0.5 ± 0.3

Shamed

0.8 ± 0.3

0.7 ± 0.4

0.5 ± 0.3

0.8 ± 0.3

Model

4.7 ± 0.8△△

4.7 ± 0.4△△

5.5 ± 0.7△△

4.8 ± 0.6△△

Sylimarin

3.5 ± 0.3*

4.4 ± 0.9

4.5 ± 0.6

4.2 ± 0.5

Berberine

2.4 ± 0.5**

2.3 ± 0.7**

2.7 ± 0.7**

2.5 ± 0.6**

CRAE

2.7 ± 0.4**

3.4 ± 0.9*

3.3 ± 0.3**

3.0 ± 0.3**

Bear Bile

3.9 ± 0.1

3.5 ± 0.4**

3.3 ± 0.6**

3.8 ± 0.4*

TUDCA

2.8 ± 0.3**

3.7 ± 0.2**

3.6 ± 0.2**

3.4 ± 0.2**

  1. △p < 0.05 when compared with normal group; △△p < 0.01 when compared with normal group; *p < 0.05 when compared with model group; **p < 0.01 when compared with model group.