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Table 1 The dose-dependent effect of BB on AST and ALT level in CCl 4 -induced acute liver toxicity in mice (n = 8, x ¯ ± s )

From: A comparative study on the hepatoprotective action of bear bile and coptidis rhizoma aqueous extract on experimental liver fibrosis in rats

Group

N

Dose(mg/kg)

AST(U/I)

ALT(U/I)

normal

8

—

99.0 ± 15.8

44.6 ± 10.6

CCl4

8

—

271.3 ± 142.0△ △

209.5 ± 153.9△ △

Silymarin

8

100

133.8 ± 49.9 **

80.4 ± 40.5 *

BB

8

10

202.5 ± 205.5

237.8 ± 383.2

BB

8

30

123.8 ± 17.7 **

63.9 ± 49.6 **

BB

8

90

119.0 ± 58.6 *

63.9 ± 37.3 **

BB

8

270

123.8 ± 22.0**

45.5 ± 12.0**

BB

8

810

127.3 ± 56.4 **

59.3 ± 25.3 **

  1. △p < 0.05 when compared with normal group; △△p < 0.01 when compared with normal group; *p < 0.05 when compared with model group; **p < 0.01 when compared with model group.
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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