Skip to main content

Table 2 MBCs of the extract, fractions, compounds from Dioscorea bulbifera and chloramphenicol on documented strains and clinical MDR isolates

From: Antibacterial activities of the extracts, fractions and compounds from Dioscorea bulbifera

Samples

Microorganisms and MBC (μg/mL) without and in the presence of PAßN (in parenthesis)*

 
 

E. coli

E. aerogenes

K. pneumoniae

P. aeruginosa

M. smegmatis

M. tuberculosis

 

ATCC8739

AG100A

AG102

ATCC13048

EA289

EA-CM64

ATCC11296

KP55

KP63

PA01

PA124

ATCC 700084

ATCC 27294

MTCS1

MTCS2

DBB

128 (128)

128 (64)

256 (256)

128 (128)

512 (512)

- (512)

256 (256)

256 (256)

256 (256)

256 (256)

256 (256)

128

128

-

128

DBB1

128 (64)

32 (16)

512 (256)

64 (64)

128 (128)

256 (128)

64 (64)

128 (128)

256 (128)

128 (128)

128 (128)

64

128

-

64

DBB2

256 (128)

32 (16)

256 (128)

64 (32)

128 (128)

256 (128)

128 (128)

128 (128)

64 (64)

64 (64)

256 (128)

128

128

128

64

1

- (256)

256 (128)

nd

- (256)

nd

nd

- (128)

- (256)

nd

nd

nd

-

nd

nd

nd

2

128 (128)

128 (64)

128 (128)

256 (128)

128 (128)

128 (128)

128 (128)

256 (128)

128 (128)

512 (128)

256 (128)

64

128

128

64

3

128 (32)

128 (32)

256 (32)

128 (32)

256 (32)

128 (32)

128 (64)

128 (64)

256 (64)

256 (64)

256 (64)

8

16

64

16

4

128 (128)

128 (64)

256 (128)

256 (128)

128 (64)

512 (128)

256 (128)

256 (128)

128 (128)

256 (128)

256 (128)

64

128

128

128

5

128 (128)

128 (128)

256 (128)

256 (128)

256 (128)

- (128)

512 (256)

512 (128)

- (128)

512 (256)

512 (128)

256

128

256

128

6

-

- (512)

-

nd (−)

nd (256)

nd

- (512)

nd (256)

nd (256)

nd (256)

nd (512)

-

nd

nd

nd

RA

8 (2)

4 (1)

32 (2)

8 (2)

- (256)

512 (16)

4 (4)

64 (8)

- (256)

256 (16)

512 (16)

1

1

128

4

  1. aTested samples [DBB: methanol extract from the bulbils of D. bulbifera; bafoudiosbulbins A (1), B (2), C (3), F (4), G (5), 2,7-dihydroxy-4-methoxyphenandhrene (6); EtOAc fraction (DBB1) and EtOAc sub-fraction C (DBB2); RA : reference andibiotics were chloramphenicol for bacteria, ciprofloxacin for M. smegmatis, isoniazid for M.tuberculosis; (−): MIC > 512 μg/mL; bThe drugs and compounds were tested in the absence or in the presence (values in braket) of PAßN at a final concendration of 20 μg/mL, as described previously[7]. At this concendration, no indrinsic effect against the various bacterial strains (included as indernal condrols in each assay without andibiotic) was observed; (nd): not determined.