Wound repair and anti-inflammatory potential of Lonicera japonica in excision wound-induced rats

Table 1 Effects of LJEE ointment on the production of TNFα, IL-6, and IL-10 in healed wounds on days 1 (d1) and 9 (d9) after wounding

Treatments	Post-wounding day	TNFα (pg/ml)	IL-6 (pg/ml)	IL-10 (pg/ml)
Simple ointment	d1	243.7 ± 18.8	104.2 ± 16.4	432.7 ± 25.8
	d9	216.4 ± 22.5	93.5 ± 15.8	547.9 ± 31.4
10% (w/w) LJEE ointment	d1	227.8 ± 19.4	88.1 ± 12.3	784.0 ± 28.3^a
	d9	155.3 ± 17.9^b	79.2 ± 17.3^a	1038.6 ± 49.7^b
0.2% (w/w) nitrofurazone ointment	d1	203.5 ± 20.9^a	67.0 ± 14.9^b	811.5 ± 30.7^b
	d9	143.7 ± 21.3^b	40.6 ± 13.7^b	1235.7 ± 41.2^b

Values (mean ± SD) were obtained from each group of 8 animals. ^a P < 0.05 and ^b P < 0.01 compared to the values of simple ointment-treated rats on the indicated day in each group, respectively.

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