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Table 4 Cytotoxicity (LD 50 in mg/mL) of extract and selectivity index based on MIC of extract after 12 hours of extracts from thirteen plants examined

From: Some southern African plant species used to treat helminth infections in ethnoveterinary medicine have excellent antifungal activities

Plant species

Cytotoxicity

A. fumigatus

C. albicans

C. neoformans

Brachylaena discolor

0.004

0.01

0.01

0.05

Zanthoxylum capense

0.008

0.2

0.05

0.1

Clerodendrum glabrum

0.172

4.3

0.55

2.15

Heteromorpha trifoliata

0.043

0.27

0.55

0.27

Apodytes dimidiata

0.003

0.01

0.01

0.04

Strychnos mitis

0.043

0.14

0.14

0.07

Maesa lanceolata

0.104

0.34

0.65

0.65

Indigofera frutescens

0.052

0.65

0.33

0.33

Leucosidea sericea

0.016

0.1

0.05

0.2

Melia azedarach

0.145

0.47

0.91

0.23

Clausena anisata

0.053

2.65

0.08

0.33

Cyathea dregei

0.017

0.11

0.01

0.11

Milletia grandis

0.021

0.53

0.13

0.03

  1. Therapeutic index calculated by dividing LD50 by MIC.