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Table 3 Effects of rutin on renal antioxidant profile

From: Protective effects of rutin against potassium bromate induced nephrotoxicity in rats

Treatment

CAT (U/min)

SOD (U/mg protein)

GSH-Px (nmol/mg protein)

GSR (nmol/min /mg protein)

GST (nmol/min/mg protein)

Control

18.2±2.2++

19.05±1.54++

45.33±1.65++

203.3±10.3 ++

123.8±13.3++

Saline (0.5 ml/kg bw; 0.9% NaCl)

18.5±2.6++

19.75±1.4++

43.5±1.35++

200.6±8.3 ++

121.8±10.3++

KBrO3 (20 mg/kg bw)

7.5±0.85**

7.58±2.08**

23.35±3.08 **

114.5±20.7**

53.8±26.1**

KBrO3+Rutin (50 mg/kg bw)

11.5±2.2*++

12.83±1.87*++

34.91±5.54 *++

158.0±10.5*++

104.8±11.5 ++

KBrO3+Rutin (70 mg/kg bw)

16.5±2.6++

17.62±2.14++

41.26±4.6++

184.5±11.3++

116.5±14.3++

Rutin alone (70 mg/kg bw)

17.37±1.17++

20.72±1.72++

46.06±2.12++

207.3±13.2++

126.2±21.5++

  1. Mean ± SEM (n=6 number).
  2. *, ** indicate significance from the control group at P<0.05 and P<0.01 probability level.
  3. ++ indicate significance from the KBrO3 group P<0.01 probability level.