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Table 3 Selected genes less expressed (log2 ≤ −1.0) during S. cerevisiae exposure to propolis according to the GO term finder enrichment analysis (for a complete list of the genes less expressed, see Additional file 1 : Table A1)

From: Transcriptional profiling of Saccharomyces cerevisiae exposed to propolis

Cell cycle (GO:0007049) and Cell cycle process (GO: 0022402) (p< 4.76x10-6)
SMC4 Subunit of the condensin complex; reorganizes chromosomes during cell division
MCM10 Essential chromatin-associated protein involved in the initiation of DNA replication
CIN8 Kinesin motor protein involved in mitotic spindle assembly and chromosome segregation
IBD2 Component of the BUB2-dependent spindle checkpoint pathway, interacts with Bfa1p and functions upstream of Bub2p and Bfa1p
BRN1 Subunit of the condensin complex; required for chromosome condensation and for clustering of tRNA genes at the nucleolus
CEP3 Essential kinetochore protein, component of the CBF3 complex that binds the CDEIII region of the centromere
SLK19 Kinetochore-associated protein required for normal segregation of chromosomes in meiosis and mitosis
NSL1 Component of the MIND kinetochore complex which joins kinetochore subunits contacting DNA to those contacting microtubules
SPC24 Component of the evolutionarily conserved kinetochore-associated Ndc80 complex
HOS2 Histone deacetylase required for gene activation via specific deacetylation of lysines in H3 and H4 histone tails
ESA1 Catalytic subunit of the histone acetyltransferase complex (NuA4) that acetylates four conserved internal lysines of histone H4
MAM1 Monopolin, kinetochore associated protein involved in chromosome attachment to meiotic spindle
Chromosome organization (GO:0051276) (p< 1.30x10 -6 )
RLF2 Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) and Msi1p that assembles newly synthesized histones
SGF29 Probable subunit of SAGA histone acetyltransferase complex
RNA metabolic process (GO:0016070) and RNA biosynthetic process (GO:0009058) (p< 0.02)
LEO1 Component of the Paf1 complex, which associates with RNA polymerase II and is involved in histone methylation
SPT21 Protein required for normal transcription at several loci including HTA2-HTB2 and HHF2-HHT2
RFM1 Specificity factor that directs the Hst1p histone deacetylase to some of the promoters regulated by Sum1p
IES2 Protein that associates with the INO80 chromatin remodeling complex under low-salt conditions
IFH1 IFH1 exhibits genetic interactions with FHL1, overexpression interferes with silencing at telomeres and HM loc
NGG1 component of transcriptional adaptor and histone acetyltransferase complexes, the ADA, the SAGA, and the SLIK complexes