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Table 1 Overrepresented categories of the significantly modulated (up- and down-regulated) genes found in the microarray hybridization based on the genome coverage (p<0.05)

From: Transcriptional profiling of Saccharomyces cerevisiae exposed to propolis

GOID

TERM

CORRECTED P-VALUE

FDR RATE

GO:0009987

cellular process

3.57E-09

0.00%

GO:0065007

biological regulation

7.91E-09

0.00%

GO:0050794

regulation of cellular process

1.58E-07

0.00%

GO:0050789

regulation of biological process

7.16E-07

0.00%

GO:0051276

chromosome organization

1.30E-06

0.00%

GO:0006996

organelle organization

2.25E-06

0.00%

GO:0071841

cellular component organization or biogenesis at cellular level

2.66E-06

0.00%

GO:0071842

cellular component organization at cellular level

3.14E-06

0.00%

GO:0022402

cell cycle process

3.16E-06

0.00%

GO:0007049

cell cycle

4.76E-06

0.00%

GO:0071840

cellular component organization or biogenesis

5.08E-06

0.00%

GO:0022403

cell cycle phase

5.56E-06

0.00%

GO:0006351

transcription, DNA-dependent

1.13E-05

0.00%

GO:0032774

RNA biosynthetic process

1.28E-05

0.00%

GO:0016043

cellular component organization

1.95E-05

0.00%

GO:0000279

M phase

1.98E-05

0.00%

GO:0007059

chromosome segregation

2.94E-05

0.00%

GO:0010556

regulation of macromolecule biosynthetic process

3.70E-05

0.00%

GO:0060255

regulation of macromolecule metabolic process

4.61E-05

0.00%

GO:0019219

regulation of nucleobase-containing compound metabolic process

4.64E-05

0.00%

GO:2000112

regulation of cellular macromolecule biosynthetic process

4.86E-05

0.00%

GO:0051171

regulation of nitrogen compound metabolic process

4.96E-05

0.00%

GO:0006807

nitrogen compound metabolic process

6.46E-05

0.00%

GO:0051252

regulation of RNA metabolic process

0.000109266

0.00%

GO:0034641

cellular nitrogen compound metabolic process

0.000114855

0.00%

GO:0006325

chromatin organization

0.00011847

0.00%

GO:0009889

regulation of biosynthetic process

0.00012496

0.00%

GO:0031326

regulation of cellular biosynthetic process

0.00012496

0.00%

GO:0000278

mitotic cell cycle

0.000140145

0.00%

GO:0006355

regulation of transcription, DNA-dependent

0.000140184

0.00%

GO:2001141

regulation of RNA biosynthetic process

0.000140184

0.00%

GO:0048285

organelle fission

0.00015597

0.00%

GO:0007067

mitosis

0.000167729

0.00%

GO:0000280

nuclear division

0.000263661

0.00%

GO:0080090

regulation of primary metabolic process

0.000279393

0.00%

GO:0006139

nucleobase-containing compound metabolic process

0.000384242

0.00%

GO:0065003

macromolecular complex assembly

0.001007045

0.00%

GO:0031323

regulation of cellular metabolic process

0.00115049

0.00%

GO:0000087

M phase of mitotic cell cycle

0.001853624

0.00%

GO:0019222

regulation of metabolic process

0.002020633

0.00%

GO:0043933

macromolecular complex subunit organization

0.002159081

0.00%

GO:0050896

response to stimulus

0.002997939

0.00%

GO:0051179

localization

0.003108437

0.00%

GO:0033043

regulation of organelle organization

0.00356682

0.00%

GO:0048523

negative regulation of cellular process

0.003751468

0.00%

GO:0010468

regulation of gene expression

0.004560142

0.00%

GO:0016568

chromatin modification

0.006683962

0.00%

GO:0048519

negative regulation of biological process

0.006744751

0.00%

GO:0034622

cellular macromolecular complex assembly

0.007563808

0.00%

GO:0006950

response to stress

0.009479328

0.00%

GO:0055085

transmembrane transport

0.011885843

0.00%

GO:0006366

transcription from RNA polymerase II promoter

0.01881881

0.00%

GO:0010604

positive regulation of macromolecule metabolic process

0.021216691

0.00%

GO:0034621

cellular macromolecular complex subunit organization

0.024007449

0.00%

GO:0016070

RNA metabolic process

0.026116229

0.00%

GO:0009058

biosynthetic process

0.028171132

0.00%

GO:0051173

positive regulation of nitrogen compound metabolic process

0.032491519

0.00%

GO:0000819

sister chromatid segregation

0.033192255

0.00%

GO:0009893

positive regulation of metabolic process

0.034622731

0.00%

GO:0031325

positive regulation of cellular metabolic process

0.035672319

0.00%

  1. Enrichment analysis was performed using the GO Term Finder available at <http://go.princeton.edu/cgi-bin/GOTermFinder> for searching for significant shared GO terms to describe the gene list of the significantly modulated genes (p<0.05). The input list for the analysis comprised 1,399 representing the total of up-and down-regulated found in the microarray analysis. FDR is the percentage of the GO terms with p-values as good as or better than a particular GO term with this FDR would be expected to be false positives.