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Table 12 Histopathological investigation of control and NK treated animals for 28 days

From: Acute toxicity and the 28-day repeated dose study of a Siddha medicine Nuna Kadugu in rats

Tissue Treatment Male Female
Brain, Eyes Control (0.5% CMC) Normal Normal
NK (900 mg/kg p.o/day) Normal Normal
Satellite - NK (900 mg/kg p.o/day) Normal Normal
Lung (right and left), Prostate, Thyroid gland, Thymus Control (0.5% CMC) Normal Normal
NK (900 mg/kg p.o/day) Normal Normal
Satellite - NK (900 mg/kg p.o/day) Normal Normal
Spinal Cord, Lymph Nodes, Muscle, Bone Control (0.5% CMC) Normal Normal
NK (900 mg/kg p.o/day) Normal Normal
Satellite - NK (900 mg/kg p.o/day) Normal Normal
Heart, Liver Control (0.5% CMC) Normal Normal
NK (900 mg/kg p.o/day) Normal Normal
Satellite - NK (900 mg/kg p.o/day) Normal Normal
Stomach, Intestine Control (0.5% CMC) Normal Normal
NK (900 mg/kg p.o/day) Normal Normal
Satellite - NK (900 mg/kg p.o/day) Normal Normal
Kidney, Adrenals, Urinary bladder Control (0.5% CMC) Normal Normal
NK (900 mg/kg p.o/day) Normal Normal
Satellite - NK (900 mg/kg p.o/day) Normal Normal
Sex organ (Testis/Epididymis) Control (0.5% CMC) Normal -
NK (900 mg/kg p.o/day) Normal -
Satellite - NK (900 mg/kg p.o/day) Normal -
Sex organ (Uterus /ovaries/) Control (0.5% CMC) - Normal
NK (900 mg/kg p.o/day) - Normal
Satellite - NK (900 mg/kg p.o/day) - Normal