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Table 4 Effect of Rutin on Indices of hepatotoxicity

From: CCl4-induced hepatotoxicity: protective effect of rutin on p53, CYP2E1 and the antioxidative status in rat

Treatment ALT (U/L) AST (U/L) ALP (U/L) γ-GT (nM/min /mg protein)
Control 52.11±2.12++ 76.32±2.74++ 198.10±3.93++ 105.25±2.22++
3 ml/kg CCl4 111.01±3.42** 234.10±4.27** 470.13±6.49** 154.03±3.02**
50 mg/kg Rutin+CCl4 58.01±2.68++ 102.13±4.99++ 227.05±3.89++ 111.03±3.04++
70 mg/kg Rutin+CCl4 56.12±2.05++ 98.61±2.75++ 209.06±3.68++ 107.23±2.01++
  1. Mean ±SE (n=6 number).
  2. ** indicate significance from the control group at P< 0.01 probability level.
  3. ++ indicate significance from the CCl4 group at P< 0.01 probability level.