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Table 5 Routine laboratory parameters: mean difference and standard deviation (SD) between treatment group (aVQ) and control group by independent t -test and result of the repeated measured analysis of variance (ANOVA, influence of treatment)
| Values at baseline (SD) | Difference between aVQ and control | ||||||
|---|---|---|---|---|---|---|---|
| aVQ | Control | t | t | t | t | F | |
| at baseline | at week 8 | at week 16 | at week 24 | ANOVA | |||
| WBCx1000/μl | 6.21 (2.13) | 5.24 (1.17) | −1.595 | −2.1951* | −2.0243 | −2.1076* | 7.614* |
| Platelets x1000/μl | 61.38 (77.07) | 72.19 (83.77) | 0.38 | −0.5491 | 0.2193 | 0.3207 | 0.0442 |
| Neutrophils % | 64.65 (8) | 63.66 (8.29) | −0.345 | −0.7475 | 1.6094 | −0.291 | 0.0055 |
| Lymphocytes % | 21.83 (6.37) | 22.94 (7.51) | 0.4493 | 2.1109* | −0.068 | 1.0294 | 1.5019 |
| Monocytes % | 7.07 (2.91) | 7.74 (3.69) | 0.5746 | 0.5052 | 0.2823 | 0.8871 | 0.776 |
| Eosinophils % | 6.08 (3.89) | 4.91 (2.39) | −1.028 | −3.677** | −3.2466** | −2.3029* | 10.1286** |
| Basophiles % | 0.37 (0.21) | 0.76 (0.63) | 2.3308* | 0.4129 | 0.0282 | −0.081 | 2.0996 |
| Protein g/dl | 6.16 (0.44) | 6.31 (0.37) | 1.0894 | 0.1437 | 0.3964 | 1.0308 | 0.4806 |
| AST U/l+ | 19.62 (4.26) | 21 (8.48) | 0.5798 | 0.4339 | 1.0689 | 0.4566 | 0.6618 |
| ALT U/l† | 19.44 (9.39) | 20.31 (11.27) | 0.2386 | 0.064 | 1.3147 | −0.0086 | 0.2651 |
| ALK U/l‡ | 65.75 (16.43) | 72.56 (48.02) | 0.5369 | −2.146* | −3.0221** | −2.8479** | 2.6545 |
| Bilirubin mg/dl | 0.84 (0.24) | 0.79 (0.28) | −0.471 | −0.1546 | −0.4448 | −0.6975 | 0.2735 |
