Table 1 Laxative effect of the crude extract of Fumaria parviflora (Fp.Cr) without and with atropine in mice
From: Species and tissue-specificity of prokinetic, laxative and spasmodic effects of Fumaria parviflora
Group No. | Treatment | Dose (mg/kg) | Mean defecation/group | Mean number of wet feces/group | Mean % of wet feces |
|---|---|---|---|---|---|
1 | Saline (p.o., ml/kg) | 10 | 3 ± 0.36 | 0 | 0 |
2 | Carbachol (i.p.) | 1 | 11.5 ± 0.5*** | 9.1 ± 0.5 | 79.5 ± 3.3 |
3 | Fp.Cr (p.o.) | 30 | 8.3 ± 0.9** | 5.2 ± 0.6 | 61.2 ± 2.2 |
4 | 100 | 11.1 ± 0.3*** | 8.0 ± 1.0 | 71.0 ± 3.2 | |
5 | Carbachol (i.p.) + Atropine (i.p.) | 1 + 10 | 4.0 ± 0.5*** | 0.3 ± 0.2 | 6.0 ± 3.8 |
6 | Fp.Cr (p.o.) + Atropine (i.p.) | 30 + 10 | 5.3 ± 0.9** | 1.5 ± 0.2 | 30.0 ± 4.3 |
7 | 100 + 10 | 4.6 ± 0.6*** | 0.5 ± 0.2 | 10.6 ± 5.0 |