Water soluble extract of P. linteus (WA) reduces IgE levels in AD induced mice. After 2 and 4 weeks of AD induction, sera were obtained from each group, and the levels of total IgE (A), antigen (mite)-specific IgE (B) and total IgG (C) were measured by ELISA. Error bars indicated S.D. One (*), two (**) and three asterisk (***) indicates P < 0.05, P < 0.005, P < 0.001, respectively. Data are representative of three independent experiments.