A and B The serum C-terminal telopeptide of type 1 collagen (CTX) and osteocalcin levels before and after treatment for all the groups. Data were presented as mean ± SEM with significant difference p < 0.05. *indicate significant difference before and after treatment. SHAM : Sham- operated group. ORX : Orchidectomized control group. ORX + T : Orchidectomized group treated by testosterone. ORX + EL : Orchidetctomized group treated with EL.