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Table 4 The effects of 80% methanolic leaf extract of Caylusea abyssinica on Oral Glucose Tolerance Test in rats

From: Evaluation of the effects of 80% methanolic leaf extract of Caylusea abyssinica (fresen.) fisch. & Mey. on glucose handling in normal, glucose loaded and diabetic rodents

 

Blood glucose level in mg/dl

Group

0 min

30 min

60 min

120 min

TW80

102.33 ± 3.20

140.50 ± 16.76a1

126.83 ± 6.55d3

90.50 ± 1.96 b2

GL5

101.83 ± 6.29

125.17 ± 11.47 a2

74.33 ± 8.72b3,c3

72.67 ± 8.79b3

CA100

116.83 ± 4.19

158.67 ± 15.34 a2

145.83 ± 7.03d3

86.67 ± 5.82b3

CA200

104.00 ± 1.98

131.50 ± 8.68a1

89.67 ± 4.90b3,c2

82.33 ± 4.45b3,e2

CA300

103.50 ± 9.21

127.17 ± 13.34a1

117.33 ± 9.06d3

100.00 ± 12.03

  1. n = 6; CA100 = C. abyssinica extract 100 mg/kg, CA200 = C. abyssinica extract 200 mg/kg, CA300 = C. abyssinica extract 300 mg/kg, TW80 = 2%Tween-80, GL5 = Glibenclamide 5 mg/kg; a compared to blood glucose levels (BGL) at 0 min, b compared with BGL after 30 min, c compared with the negative control, d compared with the positive control; 1p < 0.05, 2 p < 0.01 and 3 p < 0.001. Time refers to time after extract administration.