Reducing power and iron chelating property of Terminalia chebula (Retz.) alleviates iron induced liver toxicity in mice

Table 1 The effect of TCME on serum marker enzymes (ALAT, ASAT and ALP) and Bilirubin in iron overloaded mice

Treatment	ALAT		ASAT		ALP		Bilirubin
	Unit/L	% Change	Unit/L	% Change	Unit/L	% Change	Unit/L	% Change
B	16.87 ± 2.07	---	30.07 ± 1.77	---	133.58 ± 7.76	---	1.29 ± 0.15	---
C	36.08 ± 2.76^X2	113.79	69.8 ± 1.46^X3	132.13	398.76 ± 24.73^X2	198.51	3.21 ± 0.23^X3	147.88
S50	33.27 ± 2.91^X2	97.12	50.67 ± 3.58^X2Y2	68.51	265.11 ± 19.09^X2Y3	98.45	2.45 ± 0.19^X3Y2	88.89
S100	30.85 ± 2.53^X2	82.75	43.71 ± 1.33^X2Y3	45.35	236.08 ± 12.25^X2Y2	76.73	1.92 ± 0.19^X2Y3	48.41
S200	22.33 ± 1.99^X1Y1	32.29	37.96 ± 2.13^X2Y3	26.25	147.52 ± 12.11^Y2	10.43	1.55 ± 0.06^X1Y2	19.57
D	23.55 ± 1.39^X1Y1	39.54	44.67 ± 5.52^X1Y1	48.58	151.58 ± 9.92^X2Y2	13.47	1.59 ± 0.12^X2Y2	23.01

Values are mean ± SD of six observations.
X: significant difference from normal mice (B) group (X1: p ≤ 0.05, X2: p ≤ 0.01 and X3: p ≤ 0.001).
Y: significant difference from iron overloaded (C) group (Y1: p ≤ 0.05, Y2: p ≤ 0.01 and Y3: p ≤ 0.001).

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