Table 2 Minimum Inhibitory concentrations of costunolide and eremanthin isolated from Costus speciosus against tested fungi using microdilution technique (μg/ml)
Tested organisms | Costunolide | Eremanthin | Fluconazole | Ketoconazole |
|---|---|---|---|---|
Trichophyton mentagrophytes | 62.5 | 125 | 25 | < 12.5 |
Trichophyton simii | 31.25 | 62.5 | < 12.5 | < 12.5 |
Trichophyton rubrum 296 | 31.25 | 62.5 | < 12.5 | < 12.5 |
Trichophyton rubrum 57 | 62.5 | 250 | 25 | < 12.5 |
Epidermophyton floccosum | 125 | 125 | 12.5 | < 12.5 |
Scopulariopsis sp. | 250 | > 250 | < 12.5 | < 12.5 |
Aspergillus niger | 250 | 125 | 100 | < 12.5 |
Curvularia lunata | 125 | 250 | < 12.5 | < 12.5 |
Magnaporthe grisea | 250 | 250 | nt | nt |
Botrytis cinerea | > 250 | > 250 | nt | nt |
Candida albicans | > 250 | > 250 | > 100 | 25 |