Figure 2

Time course of the effects of 0.5 tablets of Neurexan on the spectral frequencies in four rat brain areas (frontal cortex [A], hippocampus [B], striatum [C], and reticular formation [D]). The electroencephalographic (EEG) signatures were obtained during five experimental intervals of 1 hour (1, 2, 3, 4, and 5 hours). Changes of δ-, θ-, α1-, α2-, β1-, and β2-waves are presented as percentage of predrug baseline. The data of eight rats are summarized as mean ± SEM. Significant differences to vehicle controls (0.9% NaCl) are indicated by asterisks (P < 0.01).