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Table 1 Effect of Aqueous Acetone Extracts of  Sida acuta  and  Sida cordifolia  on the haematological parameters on whole blood of rats

From: Toxicity assessment and analgesic activity investigation of aqueous acetone extracts of Sida acuta Burn f . and Sida cordifolia L. (Malvaceae), medicinal plants of Burkina Faso

Haematological parameters Group 1 Group 2 Group 3 Group 4
Sida acuta Aqueous Acetone Extract
WBC(103/μl) 12.43 ± 3.20 12.19 ± 0.10ns 11.69 ± 1.20ns 11.77 ± 0.11ns
RBC (106/μl) 7.17 ± 1.18 7.23 ± 2.36ns 7.13 ± 1.03ns 7.08 ± 0.88ns
Eosinophil (%) 2.18 ± 0.68 2.21 ± 1.08ns 2.00 ± 2.20ns 2.11 ± 4.53ns
Lymphocyte (%) 78.11 ± 0.24 77.85 ± 1.57ns 77.69 ± 1.43ns 78.00 ± 2.21ns
Neutrophil (%) 25.89 ± 0.09 25.78 ± 0.31ns 25.59 ± 1.43ns 25.81 ± 1.21ns
Monocyte (%) 1.57 ± 0.24 1.02 ± 1.20* 1.00 ± 1.43* 0.91 ± 1.21*
Basophil (%) 0.17 ± 0.09 0.13 ± 0.31ns 0.11 ± 0.43** 0.12 ± 0.22ns
Haemoglobin (g/dl) 15.23 ± 1.13 14.69 ± 0.15ns 14.21 ± 0.63* 14.11 ± 0.77 *
Haematocrit (%) 43.46 ± 2.20 44.00 ± 1.21ns 42.43 ± 3.20* 40.61 ± 1.2**
MCV (μm3) 57.00 ± 0.48 56.48 ± 1.28ns 55.35 ± 0.15* 54.79 ± 2.30**
MCH (pg) 18.87 ± 1.20 18.62 ± 0.43ns 18.90 ± 1.22ns 18.49 ± 0.67ns
MCHC (g/dl) 33.78 ± 0.11 33.35 ± 2.22ns 33.00 ± 0.40ns 33.13 ± 1.22ns
Platelet (x103/μl) 967.42 ± 4.12 961.11 ± 5.10 ns 953.22 ± 2.35 ns 964.00 ± 1.10 ns
Sida cordifolia Aqueous Acetone Extract
WBC(103/μl) 12.21 ± 2.21 12.08 ± 0.54ns 12.00 ± 1.10ns 12.02 ± 1.22ns
RBC (106/μl) 7.29 ± 0.21 7.45 ± 0.15ns 7.22 ± 0.59ns 7.10 ± 0.27ns
Eosinophil (%) 2.23 ± 1.03 2.14 ± 0.56ns 2.00 ± 0.53ns 2.17 ± 4.53ns
Lymphocyte (%) 78. 31 ± 1.03 77.60 ± 0.88ns 77.62 ± 1.20ns 76.89 ± 0.22*
Neutrophil (%) 26.13 ± 0.68 26.00 ± 1.08ns 25.78 ± 2.15ns 26.13 ± 2.33ns
Monocyte (%) 2.01 ± 0.09 0.76 ± 0.31* 0.82 ± 1.43* 0.91 ± 1.21*
Basophil (%) 0.2 ± 0.24 0.17 ± 0.10ns 0.17 ± 1.25ns 0.13 ± 0.36*
Haemoglobin (g/dl) 15.02 ± 1.43 14.40 ± 0.31ns 14.23 ± 0.54ns 14.75 ± 1.21ns
Haematocrit (%) 42.83 ± 2.21 42.60 ± 1.10ns 41.67 ± 0.33* 42.00 ± 0.22ns
MCV (μm3) 56.78 ± 0.15 56.62 ± 0.34ns 56.41 ± 2.10ns 56.80 ± 0.33ns
MCH (pg) 19.61 ± 0.24 19.57 ± 0.22ns 19.07 ± 1.20ns 19.55 ± 0.36ns
MCHC (g/dl) 33.26 ± 0.1 33.51 ± 0.54ns 33.37 ± 2.21ns 33.00 ± 0.2ns
Platelet (x103/μl) 960.11 ± 0.33 957.23 ± 0.67ns 963.47 ± 1.63ns 966.40 ± 0.67ns
  1. WBC: leucocyte count; RBC: erythrocyte count; MCV: mean corpuscular volume; MCH: mean corpuscular haemoglobin; MCHC: mean corpuscular haemoglobin concentration.
  2. Values are mean ± S.E.M. (n = 6) one-way ANOVA followed by Dunnett’s t- test: Compare all vs. control: p>0.05, *p <0.05, **p <0.01 compared with control
  3. Group 1: control, rats received 10% DMSO.
  4. Group 2: rats received 10% DMSO with extract (75 mg/kg body weight).
  5. Group 3: rats received 10% DMSO with extract (100 mg/kg body weight).
  6. Group 4: rats received 10% DMSO with extract (200 mg/kg body weight).