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Table 7 Effect of LPCE on histology of liver

From: Hepatoprotection with a chloroform extract of Launaea procumbens against CCl4-induced injuries in rats

Treatment

Fatty changes

Cellular hypertrophy and necrosis

Blood vessel congestion

Degeneration of lobules

Fibrosis

Inflammatory cell infiltrations

Control

-

-

-

-

-

-

3 ml/kg CCl4

+++

+++

+++

+++

+++

+++

100 mg/kg Silymarin+ CCl4

+

-

-

-

-

-

100 mg/kg LPCE+CCl4

-/+

-

-

-

-

-

200 mg/kgLPCE+CCl4

-/+

-

-

-

-/+

-

200 mg/k g LPCE alone

-

-

-

-

-

-

  1. -, normal; +/-, mild; ++, medium; +++, severe disruption.