|
Parameter
|
Experimental groups
|
|---|
| |
Control
|
CCE
|
CDDP 15 days
|
CDDP + CCE (pre-treatment)
|
CDDP + CCE (post-treatment)
|
CDDP 30 days
|
CDDP + CCE (pre-treatment)
|
CDDP + CCE (post-treatment)
|
|---|
|
Creatinine (mg/dl)
|
0,8 ± 0,14
|
0,75 ± 0,1
|
1,79 ± 0,0045*
|
0,56 ± 0,005*
|
0,88 ± 0,0048*
|
2,13 ± 0,005*
|
0,87 ± 0,0044
|
0,95 ± 0,0052
|
|
Urea (mg/dl)
|
52,34 ± 0,12
|
51,54 ± 0,17
|
79,13 ± 0,12*
|
58,5 ± 0,14*
|
60,13 ± 0,19*
|
94,2 ± 0,12*
|
60,12 ± 0,18
|
68,5 ± 0,15
|
|
Albumin (g/dl)
|
10,44 ± 0,14
|
10,72 ± 0,15
|
8,01 ± 0,17*
|
9,8 ± 0,14*
|
8,48 ± 0,18*
|
7,12 ± 0,16*
|
9,91 ± 0,12
|
9,24 ± 0,16
|
|
Total protein (g/dl)
|
9,95 ± 0,19
|
9,78 ± 0,21
|
7,12 ± 0,25*
|
8,67 ± 0,19*
|
8,03 ± 0,26*
|
6,2 ± 0,193*
|
8,7 ± 0,23
|
8,12 ± 0,26
|
- Experimental values are expressed as mean ± SD. Comparison of mean values between groups was performed by one way-analysis of variance (oneway-ANOVA) (*) significantly different from control at p<0.05.
