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Table 3 Effect of CCE on several serum parameters with/without CDDP treatment

From: Protective effect of cactus cladode extract against cisplatin induced oxidative stress, genotoxicity and apoptosis in balb/c mice: combination with phytochemical composition

Parameter

Experimental groups

 

Control

CCE

CDDP 15 days

CDDP + CCE (pre-treatment)

CDDP + CCE (post-treatment)

CDDP 30 days

CDDP + CCE (pre-treatment)

CDDP + CCE (post-treatment)

Creatinine (mg/dl)

0,8 ± 0,14

0,75 ± 0,1

1,79 ± 0,0045*

0,56 ± 0,005*

0,88 ± 0,0048*

2,13 ± 0,005*

0,87 ± 0,0044

0,95 ± 0,0052

Urea (mg/dl)

52,34 ± 0,12

51,54 ± 0,17

79,13 ± 0,12*

58,5 ± 0,14*

60,13 ± 0,19*

94,2 ± 0,12*

60,12 ± 0,18

68,5 ± 0,15

Albumin (g/dl)

10,44 ± 0,14

10,72 ± 0,15

8,01 ± 0,17*

9,8 ± 0,14*

8,48 ± 0,18*

7,12 ± 0,16*

9,91 ± 0,12

9,24 ± 0,16

Total protein (g/dl)

9,95 ± 0,19

9,78 ± 0,21

7,12 ± 0,25*

8,67 ± 0,19*

8,03 ± 0,26*

6,2 ± 0,193*

8,7 ± 0,23

8,12 ± 0,26

  1. Experimental values are expressed as mean ± SD. Comparison of mean values between groups was performed by one way-analysis of variance (oneway-ANOVA) (*) significantly different from control at p<0.05.
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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