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Table 1 Expression of selected genes exhibiting > 1.5-fold or < 0.67-fold changes in Drosophila S2 cells after exposure to 100 μM PA for 2h

From: Pharmacological modulation of histone demethylase activity by a small molecule isolated from subcritical water extracts of Sasa senanensis leaves prolongs the lifespan of Drosophila melanogaster

Accession number

Gene symbol

Gene description

Fold change

Up-regulated genes

   

NM_001103559

CG34330

_

10.0

NM_001038793

CG

_

3.78

NM_057233

impL3

lactic DH

3.78

NM_141268

Hph

fatiga

2.99

NM_001103964

CG9815

_

2.93

NM_140239

CG11652

_

2.82

NM_080713

fok

fledgling of Klp38B

2.80

NM_057947

Thor

eukaryotic initiation factor 4E-binding protein

2.26

NM_001144611

bnl

fibroblast growth factor

2.24

NM_058032

Fpps

Famesyl diphosphate synthase

2.15

Nm_079270

Hsp67Bc

Gene 3

2.07

NM_137458

Dgp-1

Dgp-1

2.02

NM_080173

GstD2

Glutathione S transferase D2

1.81

NM_170034

Gclm

Glutathione-cysteine ligase modifier submit

1.81

NM_138269

cue

cueball

1.68

NM_135115

CG14005

_

1.67

NM_001032272

CG3785///CG33786

_///_

1.65

NM_001170286

_

_

1.64

NM_001031943

Hsp22///Hsp67Bb

heat shock protein hsp22///Gene 2

1.63

NM_143700

CG17724///seq

_///sequoia

1.63

NM_141334

CG10979

_

1.61

NM_134584

CG32512

_

1.61

NM_001043271

SNF4Agamma

Lochrig

1.61

NM_140199

scyl

scylla

1.59

NM_144004

CG3348

_

1.58

NM_206410

asaragine-synthetase

asparagine synthetase

1.57

NM_135328

Spn28D

Dm-serpin-28D

1.57

NM_001144540

CG2017

GP-1 related

1.55

NM_137485

GstE7

Glutathione S transferase E7

1.52

Down-regulated genes

   

NM_138240

CG9194

_

0.55

NM_143815

Invadolysin

invadolysin

0.59

NM_140792

MYPT-75D

MYPT-75D

0.59

NM_136764

wde

Windei

0.60

NM_057696

Ret

Ret oncogene

0.60

NM_079534

alpha-Est 9

fragment J

0.62

NM_130578

CG32809

_

0.62

NM_079937

sls

sallimus

0.62

NM_001014750

mnb

minibrain

0.62

NM_079578

jumu

Domina

0.63

NM_080370

ltd

lightoid

0.63

NM_001103650

Btk29A

Btk family kinase at 29A

0.63

NM_168566

CG32135

_

0.63

NM_206332

Muc68Ca

Muc in 68Ca

0.64

NM_001031884

CG33691///CG33692

///

0.64

NM_176545

unk

unkempt

0.65

NM_168366

CG42268

CG32044

0.65

NM_001169959

Sema-5c

Semaphorin 5C

0.65

NM_078959

Prx2540-2

peroxiredoxin 2540

0.66

NM_001104450

jigr1

CG17383

0.66

NM_001169949

Pi3K68D

dPI 3-kinase

0.66

NM_001169228

fs(1)h

rancor

0.66

NM_078607

dah

Apodystrophin

0.67

NM_137485

GstE7

Glutathione S transferase E7

1.52

  1. Fold changes relative to vehicle-treated cells. Genes were differentially transcribed at p<0.05 (t-test).