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Table 3 Histopathological evaluation of wound healing parameters on healed wounds of the vehicle-, povidone-iodine-, 1% extract- and 2% extract-treated animals

From: Potential dermal wound healing agent in Blechnum orientale Linn

Groups

Collagen formation

Fibroblast proliferation

Angiogenesis

Epithelization

Vehicle

+

+

++

+

Povidone-iodine

+++

+++

++

+++

1% extract

++

++

++

++

2% extract

+++

+++

+++

+++

  1. Sections were scored from light (+), moderate (++) or intense (+++) based on relative intensity of the blue coloration in the MT stained sections (for collagen evaluation), the relative density of fibroblast cells and blood capillaries in the H&E stained sections (for fibroblast proliferation and angiogenesis) and the complete formation of epidermis in the H&E stained sections (for epithelization).