Skip to main content

Table 4 Effects of MCL on hepatic protein, lipid peroxidation (TBARS), glutathione (GSH) and hydrogen peroxide (H2O2)

From: Hepatoprotective effects of methanol extract of Carissa opaca leaves on CCl4-induced damage in rat

Group Protein (μg/mg tissue) TBARS (nM/mg protein) GSH (μg/mg protein) H2O2 (nM H2O2/min/mg tissue)
I 1.598 ± 0.034+ 3.67 ± 0.53+ 21.34 ± 1.10+ 1.594 ± 0.016+
II 0.976 ± 0.023* 6.21 ± 0.98* 11.56 ± 1.67* 2.984 ± 0.077*
III 1.501 ± 0.081*+ 4.32 ± 0.91*+ 17.67 ± 1.16*+ 1.710 ± 0.067*+
IV 1.492 ± 0.009*+ 4.51 ± 0.74*+ 18.48 ± 1.21*+ 1.640 ± 0.053*+
V 1.685 ± 0.014+ 3.53 ± 0.42+ 20.68 ± 1.12+ 1.521 ± 0.043+
  1. Group I: Control (Olive oil+ DMSO); II: CCl4 (0.5 ml/kg bw); III: MCL (200 mg/kg bw)+CCl4 (0.5 ml/kg bw); IV: Silymarin (50 mg/kg bw)+CCl4 (0.5 ml/kg bw); V: MCL (200 mg/kg bw).
  2. MCL; methanol extract of Carissa opaca leaves
  3. Values are Mean ± SD (06 number)
  4. *, Indicate significance from control group (P < 0.05)
  5. +, Indicate significance from CCl4 group (P < 0.05)