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Table 3 Effects of MCL on hepatic antioxidant profile in rat

From: Hepatoprotective effects of methanol extract of Carissa opaca leaves on CCl4-induced damage in rat

Group

CAT (U/min)

POD (U/min)

SOD (U/mg protein)

GST (μM CDNB conjugate/min/mg protein)

GSH-Px (nM of NADPH/min/mg protein)

GSR (nM of NADPH/min/mg protein)

QR (nM of DCPIP reduced/min/mg protein)

I

4.59 ± 0.57+

10.34 ± 0.67+

3.62 ± 0.23+e

167.89 ± 9.67+

125.91 ± 5.12+

220.78 ± 10.96+

108.53 ± 6.06+

II

2.15 ± 0.74*

5.23 ± 0.45*

0.98 ± 0.09*

98.76 ± 7.45*

70.84 ± 4.68*

134.74 ± 9.72*

58.60 ± 3.53*

III

4.12 ± 0.35*+

9.87 ± 0.52*+

3.11 ± 0.14*+

150.78 ± 6.99*+

112.79 ± 5.02*+

194.23 ± 8.90*+

89.80 ± 4.08*+

IV

3.99 ± 0.64*+

9.34 ± 0.78*+

2.98 ± 0.04*+

154.23 ± 7.83*+

110.56 ± 4.81*+

189.48 ± 12.49*+

89.24 ± 5.21*+

V

4.62 ± 0.26+

10.52 ± 0.67+

3.65 ± 0.16+

168.25 ± 6.48+

122.34 ± 4.67+

223.56 ± 7.68+

110.43 ± 4.57+

  1. Group I: Control (Olive oil+ DMSO); II: CCl4 (0.5 ml/kg bw); III: MCL (200 mg/kg bw)+CCl4 (0.5 ml/kg bw); IV: Silymarin (50 mg/kg bw)+CCl4 (0.5 ml/kg bw); V: MCL (200 mg/kg bw).
  2. MCL; methanol extract of Carissa opaca leaves
  3. Values are Mean ± SD (06 number)
  4. *, Indicate significance from control group (P < 0.05)
  5. +, Indicate significance from CCl4 group (P < 0.05)