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Table 3 Effects of MCL on hepatic antioxidant profile in rat

From: Hepatoprotective effects of methanol extract of Carissa opaca leaves on CCl4-induced damage in rat

Group CAT (U/min) POD (U/min) SOD (U/mg protein) GST (μM CDNB conjugate/min/mg protein) GSH-Px (nM of NADPH/min/mg protein) GSR (nM of NADPH/min/mg protein) QR (nM of DCPIP reduced/min/mg protein)
I 4.59 ± 0.57+ 10.34 ± 0.67+ 3.62 ± 0.23+e 167.89 ± 9.67+ 125.91 ± 5.12+ 220.78 ± 10.96+ 108.53 ± 6.06+
II 2.15 ± 0.74* 5.23 ± 0.45* 0.98 ± 0.09* 98.76 ± 7.45* 70.84 ± 4.68* 134.74 ± 9.72* 58.60 ± 3.53*
III 4.12 ± 0.35*+ 9.87 ± 0.52*+ 3.11 ± 0.14*+ 150.78 ± 6.99*+ 112.79 ± 5.02*+ 194.23 ± 8.90*+ 89.80 ± 4.08*+
IV 3.99 ± 0.64*+ 9.34 ± 0.78*+ 2.98 ± 0.04*+ 154.23 ± 7.83*+ 110.56 ± 4.81*+ 189.48 ± 12.49*+ 89.24 ± 5.21*+
V 4.62 ± 0.26+ 10.52 ± 0.67+ 3.65 ± 0.16+ 168.25 ± 6.48+ 122.34 ± 4.67+ 223.56 ± 7.68+ 110.43 ± 4.57+
  1. Group I: Control (Olive oil+ DMSO); II: CCl4 (0.5 ml/kg bw); III: MCL (200 mg/kg bw)+CCl4 (0.5 ml/kg bw); IV: Silymarin (50 mg/kg bw)+CCl4 (0.5 ml/kg bw); V: MCL (200 mg/kg bw).
  2. MCL; methanol extract of Carissa opaca leaves
  3. Values are Mean ± SD (06 number)
  4. *, Indicate significance from control group (P < 0.05)
  5. +, Indicate significance from CCl4 group (P < 0.05)