Hepatoprotective effects of methanol extract of Carissa opaca leaves on CCl4-induced damage in rat

Table 2 Effects of MCL on liver function tests in rat

Group	AST(U/l)	ALT(U/l)	ALP(U/l)	γ-GT(U/l)	LDH (U/l)
I	104.12 ± 8.2+	69.9 ± 6.8+	146.34 ± 14.2+	2.01 ± 0.86+	46.7 ± 4.16+
II	211.56 ± 18.3*	221.6 ± 24.7*	315.67 ± 19.2*	4.61 ± 0.48*	133.9 ± 14.12*
III	111.61 ± 8.2*+	85.6 ± 6.8*+	188.39 ± 14.8*+	2.39 ± 0.65*+	61.8 ± 6.27*+
IV	123.76 ± 9.4*+	87.9 ± 7.7*+	201.45 ± 16.8*+	2.69 ± 0.79*+	64.32 ± 7.82*+
V	101.24 ± 8.5+	74.6 ± 6.6+	152.54 ± 16.4+	1.92 ± 0.53+	38.65 ± 3.44+

Group I: Control (Olive oil+ DMSO); II: CCl₄ (0.5 ml/kg bw); III: MCL (200 mg/kg bw)+CCl₄ (0.5 ml/kg bw); IV: Silymarin (50 mg/kg bw)+CCl₄ (0.5 ml/kg bw); V: MCL (200 mg/kg bw).
MCL; methanol extract of Carissa opaca leaves
Values are Mean ± SD (06 number)
*, Indicate significance from control group (P < 0.05)
+, Indicate significance from CCl₄ group (P < 0.05)

ISSN: 2662-7671