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Table 2 Effect of dose and sex on organ relative weights of rats in sub-acute toxicity studies of the ethyl acetate extract from C. bauchiense

From: Antibacterial and dermal toxicological profiles of ethyl acetate extract from Crassocephalum bauchiense (Hutch.) Milne-Redh (Asteraceae)

Sex

 

Relative organ weight (g/g of tissue)

 

Dose (mg/kg)

liver

kidney

heart

spleen

lung

 

0

3.34 ± 0.22

0.85 ± 0.02

0.30 ± 0.01

0.39 ± 0.18

0.60 ± 0.09

Female

30

3.22 ± 0.37

0.88 ± 0.14

0.29 ± 0.08

0.35 ± 0.12

0.64 ± 0.12

 

300

3.18 ± 0.16

0.89 ± 0.07

0.27 ± 0.02

0.38 ± 0.05

0.72 ± 0.21

 

1200

3.16 ± 0.12

0.93 ± 0.03

0.28 ± 0.10

0.33 ± 0.04

0.63 ± 0.09

 

2400

3.17 ± 0.28

0.94 ± 0.06

0.29 ± 0.03

0.40 ± 0.12

0.73 ± 0.14

 

0

3.05 ± 0.22

0.81 ± 0.09

0.29 ± 0.03

0.32 ± 0.06

0.64 ± 0.08

 

30

2.85 ± 0.01

0.83 ± 0.07

0.28 ± 0.02

0.37 ± 0.02

0.68 ± 0.02

Male

300

3.05 ± 0.34

0.83 ± 0.09

0.26 ± 0.01

0.36 ± 0.02

0.69 ± 0.10

 

1200

3.07 ± 0.17

0.93 ± 0.29

0.27 ± 0.02

0.33 ± 0.04

0.69 ± 0.06

 

2400

2.96 ± 0.09

0.94 ± 0.03

0.27 ± 0.01

0.39 ± 0.09

0.69 ± 0.06

  1. Data are expressed as Mean ± S.E.M. n = 5. Waller-Duncan test (P < 0.05).