Rectal gel application of Withania somnifera root extract expounds anti-inflammatory and muco-restorative activity in TNBS-induced Inflammatory Bowel Disease

Table 1 Comparative Antioxidant Free radical scavenging and anti-inflammatory activity of Withania somnifera

	% LPO Inhibition		% NO Scavenging	% H₂O₂ Scavenging	Reducing power
Conc. (μg/ml)	Withania somnifera	Ascorbic acid	Withania somnifera	Withania somnifera	Withania somnifera	Ascorbic acid
100	12.67 ± 0.83	85.71 ± 0.72	10.55 ± 0.97	59.84 ± 0.79	0.4996 ± 1.34	0.4177 ± 1.53
200	51.73 ± 1.26	91.54 ± 0.98	14.30 ± 0.86	63.52 ± 0.85	0.5247 ± 1.21	0.5647 ± 1.04
300	65.02 ± 1.13	96.05 ± 0.86	14.41 ± 0.93	73.59 ± 0.98	0.6137 ± 0.95	0.6804 ± 1.02
400	75.70 ± 1.23	99.09 ± 0.84	14.75 ± 0.96	76.30 ± 1.13	0.7053 ± 0.89	0.7106 ± 1.21
500	95.59 ± 0.56	99.97 ± 1.36	14.77 ± 1.13	81.79 ± 1.23	0.7972 ± 0.58	0.8090 ± 0.96

ISSN: 2662-7671