TY - JOUR AU - Pawar, Pankaj AU - Gilda, Suhit AU - Sharma, Siddhesh AU - Jagtap, Suresh AU - Paradkar, Anant AU - Mahadik, Kakasaheb AU - Ranjekar, Prabhakar AU - Harsulkar, Abhay PY - 2011 DA - 2011/04/28 TI - Rectal gel application of Withania somnifera root extract expounds anti-inflammatory and muco-restorative activity in TNBS-induced Inflammatory Bowel Disease JO - BMC Complementary and Alternative Medicine SP - 34 VL - 11 IS - 1 AB - Inflammatory Bowel Disease (IBD) is marked with chronic inflammation of intestinal epithelium driven by oxidative stress. Traditional treatments with plant extracts gained renewed interest due to their ability to ameliorate the multi factorial conditions like inflammation. We investigated the beneficial effects of Withania somnifera in Trinitro Benzyl Sulfonic Acid (TNBS) induced experimental IBD through a rectally applicable formulation. SN - 1472-6882 UR - https://doi.org/10.1186/1472-6882-11-34 DO - 10.1186/1472-6882-11-34 ID - Pawar2011 ER -